Rachel Jones Lipinski, PhD


M.Sci. 2009, Chemistry with Research Abroad; Imperial College London, UK

Ph.D. 2014, Organic Chemistry, Laboratory of M. Carmen Galan, University of Bristol, UK

Postdoc, 2013-2016, University of Florida, USA

Postdoc, 2016-current, Medical College of Wisconsin, USA


Nord JA, Wynia-Smith SL, Gehant AL, Jones Lipinski RA, Naatz A, Rioja I, Kumar Prinja R, Corbett JA, Smith BC. N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells. Frontiers in Endocrinology. 2022: 13:923925. DOI: 10.3389/fendo.2022.923925.

Jones Lipinski RA, Thillier Y, Morisseau C, Sebastiano Jr CS, Smith BC, Hall CD, Katritzky AR. Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/COX-2 inhibitors with potentially reduced gastric toxicityChem Biol Drug Des. 2021, 98(1) 102-113. doi: 10.1111/cbdd.13855. PMID: 33955172; PMCID: PMC8281356.

Waas M, Snarrenberg ST, Littrell J, Jones Lipinski RA, Hansen PA, Corbett JA, Gundry RL. SurfaceGenie : a web-based application for prioritizing cell-type-specific marker candidatesBioinformatics. 2020, 36:11, 3447-3456.

Waas M, Pereckas M, Jones Lipinski RA, Ashwood C, Gundry RL. SP2: rapid and automatable contaminant removal from peptide samples for proteomic analyses. J. Proteome Res. 2019, 18, 1644-1656.

Bongard R, Lepley M, Gastonguay A, Syrlybaeva RR, Talipov MR, Jones Lipinski RA, Leigh N, Brahmbhatt J, Kutty R, Rathore R, Ramchandran R, Sem D. Discovery and characterization of halogenated xanthene inhibitors of DUSP5 as potential photodynamic therapeutics. J. Photochem. Photobiol. A 2019, 375, 114-131.

Zhou Y, Wang Y, Zhang X, Bhar S, Jones Lipinski RA, Han J, Feng L, Butcher RA. Biosynthesis of indole-modified ascaroside pheromones in C. elegans. eLife, 2018, 7, e33286.

Zhang X, Wang Y, Perez D, Jones Lipinski RA, Butcher RA. Acyl-CoA oxidases fine-tune the production of ascaroside pheromones with specific side chain lengths. ACS Chem. Biol. 2018, 13, 1048-1056.

Panda SS,Jones RA,Bachawala P, Mohapatra PP. Spirooxindoles as potential pharmacophores. Mini-Rev. in Med. Chem. 2017, 17, 1515-1536. #Authors contributed equally to the manuscript

Kutty RG, Talipov MR, Bongard RD, Jones Lipinski RA, Sweeney NL, Sem DS, Rathore R, Ramchandran R. Dual specificity phosphatase 5-substrate interaction: a mechanistic perspective in Comprehensive, 2017, 7, 1449-1461. Book chapter.

Bongard RD, Lepley M, Thakur K, Talipov MR, Nayak J, Jones Lipinski RA, Bohl C, Sweeney N, Ramchandran R, Rathore R, Sem DS. Serendipitous discovery of light-induced (in situ) formation of an azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor. BMC Biochemistry, 2017, 18:10.

Zhang X, Li K, Jones RA, Bruner SD, Butcher RA. Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in C. elegans. Proc. Natl. Acad. Sci. USA, 2016,113, 10055-10060.

Jones RA,* Panda SS, Hall CD. Quinine conjugates and quinine analogues as potential antimalarial agents. Review. Eur. J. Med. Chem. 2015, 97, 335-355. *Co-corresponding author

Panda SS, Jones RA,Hall CD, Katritzky AR, Applications of chemical ligation in peptide synthesis via acyl transfer in Protein Ligation and Total Synthesis I, Top. Curr. Chem, 2015, 362, 229-265. Book chapter.

Han S, Jones RA, Quiclet-Sire B, Zard SZ. A convergent route to functional protected amines, diamines, and β-amino acids. Tetrahedron. 2014, 70, 7192-7206.

Barbakadze NN, Jones RA, Rosario NR, Nadaraia NSh, Kakhabrishvili ML, Hall CD, Katritzky AR. Chemical modification of oxides with N-protected amino acids. Tetrahedron 2014, 70, 7181-7184.

Jones RA,* Thillier Y, Rosario NR, Panda SS, Hall CD, Katritzky AR. Synthesis of glucosamine-NSAID bioconjugatesOrg. Biol. Chem. 2014, 12, 8325-8335.*Co-corresponding author

Benito-Alifonso D, Jones RA, Tran A-T, Woodward H, Smith N, Galan MC. Synthesis of mucin-type O-glycan probes as aminopropyl glycosidesBeilstein J. Org. Chem. 2013, 9, 1867-1872.

Galan MC, Jones RA, Tran A-T. Recent developments of ionic liquids in oligosaccharide synthesis: the sweet side of ionic liquids. Review. Carbohydr. Res. 2013, 375, 35-46.

Tran A-T, Jones RA, Boisson J, Pasteur J, Smith N, Galan MC. Copper (II) triflate: a versatile catalyst for the one-pot preparation of orthogonally protected glycosides. Adv. Synth. Catal. 2011, 353, 2593-2598.

Jones RA, Davidson R, Tran A-T, Smith N, Galan MC. Iodine-catalyzed one-pot acetalation-esterification reaction for the preparation of orthogonally protected glycosides. Carbohydr. Res. 2010, 345, 1842-1845.
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