Josh Nord, Ph.D.
Research Scientist
jnord@mcw.edu
EDUCATION AND TRAINING
B.S. 2011, Biomedical Sciences; Concordia University of Wisconsin
Ph.D. 2019, Cell and Developmental Biology, Laboratory of Lisa Cirillo, Medical College of Wisconsin
PUBLICATIONS
Nord JN, Makowski SJ, Sidlowski PFW, Bursch KL, Corbett JA, and Smith BC. BET bromodomain inhibitors attenuate transcription of a subset of IL-1-induced NF-kB targets that promote inflammation in β-cells. Journal of Biological Chemistry (2025). doi: 10.1016/j.jbc.2025.110358. PMID: 40505864.
Naatz A, Bohl KS, Jones Lipinski RA, Nord JA, Gehant AL, Hansen PA, Smith BC, and Corbett JA. Role of SIRT3 in the regulation of Gadd45α expression and DNA repair in β-cells. Journal of Biological Chemistry (2025). doi: 10.1016/j.jbc.2025.108451. PMID: 40147772.
Jones Lipinski RA, Stancill JS, Nuñez R, Wynia-Smith SL, Sprague DJ, Nord JA, Bird A, Corbett JA, Smith BC. Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology. (2024). doi: 10.1152/ajpregu.00259.2023. PMID: 38618911
Nord JA, Wynia-Smith SL, Gehant AL, Jones Lipinski RA, Naatz A, Rioja I, Kumar Prinja R, Corbett JA, Smith BC. N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells. Frontiers in Endocrinology. 2022: 13:923925. DOI: 10.3389/fendo.2022.923925.
Nghiem-Rao TH, Pfeifer C, Asuncion M, Nord J, Schill D, Pulakanti K, Patel SB, Cirillo LA, Rao S. Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver. Sci Rep. 2021 Jun 11;11(1):12386. PMCID: PMC8196029
Nord J, Schill D, Pulakanti K, Rao S, and Cirillo LA. The transcription factor FoxO1 is required for the establishment of the human definitive endoderm. bioRxiv 2020.12.22.423976; doi: 10.1101/2020.12.22.423976
Schill D, Nord J, Cirillo LA. FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes. Biochem Cell Biol. 2019 Apr;97(2):118-129. PMID: 30142277.
McGivern JV, Patitucci TN, Nord JA, Barabas MA, Stucky CL, Ebert AD. Spinal muscular atrophy astrocytes exhibit abnormal
calcium regulation and reduced growth factor production. Glia. 2013 Sep;61(9):1418-1428. PMCID: PMC3941074.
